解剖学杂志Issue(3)：261-264,389,5.DOI:10.3969/j.issn.1001-1633.2015.03.001
三种经典钙黏蛋白分子在鸡胚脊髓发育过程中的表达模式❋
Expression patterns of three classical cadherins in the spinal cord during chicken embryonic development
摘要
Abstract
Obj ective :To clarify the regulated spatiotemporal expression patterns of N-cadherin,cadherin-6 and cadherin-7 in the spinal cord during chicken embryonic development.Methods :Spinal cords at E3,E4,E5 ,E6,E8 and E10 were collected during chicken embryonic development.The expression patterns of N-cadherin,cadherin-6 and cadherin-7 were investigated with in situ hybridization in the spinal cord at different embryonic stages.Results :From E3 to E6,the signal of N-cadherin was detected in the neuroepithelium,dermatome,notochord,roof plate,floor plate and dorsal root ganglion.It was mainly expressed in the gray matter from E8 to E10.Cadherin-6 was mainly expressed in the dermatome,roof plate and floor plate from E3 to E5 .Then the positive signal was mainly exhibited in the motor column.Cadherin-7 was mainly expressed in the dermatome,floor plate,dorsal domain of the basal plate,motor column,and dorsal and ventral roots at early stages. Cadherin-7 was mainly expressed in the gray matter and ventral root from E8 to E10.Conclusion:Different expression patterns of N-cadherin,cadherin-6 and cadherin-7 mean their diverse roles in the spinal cord and its surrounding tissues during chicken embryonic development.关键词
神经钙黏蛋白/钙黏蛋白 6/钙黏蛋白 7/原位杂交/表达模式Key words
N-cadherin/cadherin-6/cadherin-7/in situ hybridization/expression pattern引用本文复制引用
李晗,杨慈清,乔梁,张必超,于亚楠,林俊堂..三种经典钙黏蛋白分子在鸡胚脊髓发育过程中的表达模式❋[J].解剖学杂志,2015,(3):261-264,389,5.基金项目
国家自然科学基金(31440049) （31440049）
新乡医学院2013年研究生科研创新支持计划资助项目(YJSCX201312Z) （YJSCX201312Z）
新乡医学院科研培育基金(2013QN125) （2013QN125）
