寄生虫与医学昆虫学报Issue(4)：244-248,5.DOI:10.3969/j.issn.1005-0507.2014.04.005
鸡感染巨型艾美耳球虫后的体液、粘膜与细胞免疫应答
THE HUMORAL,MUCOSAL AND CELLULAR IMMUNE RESPONSES OF CHICKENS INFECTED WITH EIMERIA MAXIMA
摘要
Abstract
Eimeria maxima is the most immunogenic species within the 7 eimerian parasites of chickens.To study the immune responses of chickens infected with E.maxima, humoral IgY, intestinal mucosa IgA and splenic T cell responses were detected in chickens infected with 3 doses of sporulated oocysts.When comparing to the non-infected chickens, significantly higher level of E.maxima-specific antibodies, i.e., sera IgY, biliary and intestinal sIgA were detected in infected chickens, as well as more IFN-γ-releasing T lymphocytes detected by ELISPOT.We also found that very few oocysts were detected in the feces after the tertiary infection.All these results together demonstrated that E.maxima infection can elite potent immune protection against homologous infection.关键词
巨型艾美耳球虫/免疫原性/酶联免疫斑点法/细胞免疫/抗体应答Key words
Eimeria maxima/Immunogenicity/ELISPOT/Cellular immune responses/Antibody responses引用本文复制引用
任超,赵世云,刘贤勇..鸡感染巨型艾美耳球虫后的体液、粘膜与细胞免疫应答[J].寄生虫与医学昆虫学报,2014,(4):244-248,5.基金项目
国家自然科学基金项目（No．31001060；31472180）；天津农学院科技发展基金项目 （）
