江苏大学学报（医学版）Issue(3)：217-220,4.DOI:10.13312/j.issn.1671-7783.y150016
两种图像重建算法对实验肿瘤模型的18 F-脱氧葡萄糖 PET／CT 定量结果的影响
Effect of two image reconstruction algorithms on the quantification analysis of experimental animal tumor model with 18 F-FDG PET/CT
刘平安 1万良荣 2黄钢 2孙晓光 2马玉波1
作者信息
- 1. 上海交通大学医学院附属第九人民医院核医学科，上海 200011
- 2. 上海交通大学医学院附属仁济医院核医学科，上海 200001
- 折叠
摘要
Abstract
Objective:To compare the effect of image reconstruction algorithms on the quantification a-nalysis of experimental animal tumor model with 1 8 F-FDG PET/CT.Methods:Dynamic scans with1 8 F-FDG PET/CT were performed in five New Zealand rabbits bearing VX2 tumor in fore limbs,tumor dynamic ima-ges were obtained and reconstructed with both filtered back projection method (FBP)and ordered-subset expectation maximization algorithm (OSEM).Quantification parameters of Ki and SUVmax were calculated and compared.Results:More noise presented in the images reconstructed by FBP than that by OSEM.Ki and SUVmax calculated by both reconstruction algorithms correlated well (r≥0.95);Ki and SUVmax cal-culated from images reconstructed by OSEM(Ki:0.03 ±0.01 3;SUVmax:4.89 ±1 .69)were significantly higher than that by FBP(Ki:0.025 ±0.01 1 ;SUVmax:4.1 4 ±1 .42),all P <0.05.Conclusion:Recon-struction algorithms had effect on the quantification measures,and parameters calculated from image recon-structed by OSEMwas higher than that by FBP.关键词
体层摄影术/发射型计算机/脱氧葡萄糖/图像重建Key words
tomography/dynamic PET/FDG/image reconstruction分类
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刘平安,万良荣,黄钢,孙晓光,马玉波..两种图像重建算法对实验肿瘤模型的18 F-脱氧葡萄糖 PET／CT 定量结果的影响[J].江苏大学学报（医学版）,2015,(3):217-220,4.
