血浆 miRNA-155和 miRNA-625用于非小细胞肺癌诊断的临床评价OACSTPCD
Clinical utility of plasma miRNA-155 and miRNA-625 detection in the diagnosis of non-small cell lung cancer
目的:探讨测定患者血浆 miRNA-155和 miRNA-625表达水平用于非小细胞肺癌(non-small cell lung cancer, NSCLC)临床诊断的可行性。方法:应用荧光定量 RT-PCR 法检测49例 NSCLC 患者及55例肺部良性疾病患者血浆中 miRNA-155和 miRNA-625的表达水平。构建受试者工作特征(ROC)曲线,根据这两个 miRNAs 的 ROC 曲线下面积判断其诊断 NSCLC 的效能,并与血清癌胚…查看全部>>
Objective:To evaluate the clinical utility of plasma miRNA-1 55 and miRNA-625 expression as molecular markers in the diagnosis of non-small cell lung cancer(NSCLC).Methods:Fluorescent quan-titative RT-PCR was used to detect the expressions of miRNA-1 55 and miRNA-625 in plasma samples from 49 patients with NSCLC and 55 patients with benign lung disease(BLD).Receiver operating characteristics (ROC)curves of the two miRNAs were constructed to assess diagnostic…查看全部>>
费玲;李坚;朱立欢;林杰;何清
江苏大学附属医院呼吸内科,江苏 镇江 212001江苏大学附属医院呼吸内科,江苏 镇江 212001江苏大学附属医院呼吸内科,江苏 镇江 212001解放军101医院检验科,江苏 无锡 214001解放军101医院检验科,江苏 无锡 214001
医药卫生
非小细胞肺癌miRNA-155miRNA-625血浆诊断
non-small cell lung cancermiRNA-1 55miRNA-625plasmadiagnosis
《江苏大学学报(医学版)》 2015 (3)
236-240,245,6
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