计算机应用与软件Issue(6)：5-8,13,5.DOI:10.3969/j.issn.1000-386x.2015.06.002
两序列比对算法与软件研究进展
RESEARCH PROGRESS IN PAIRWISE SEQUENCE ALIGNMENT ALGORITHMS AND THEIR SOFTWARE
摘要
Abstract
Pairwise sequence alignment is a fundamental sequence analysis method,and is widely used for similarity analysis among se-quences and homologue search in database.So far,there are more than one hundred software produced for pairwise sequence alignment.They adopts different algorithms or targets at different types of sequence.What’s more,they have great diversity in running speed and the quality of alignment result.It is essential to choose the proper software according to the situation of the sequence to be aligned and the goal to achieve. In this paper,we classify and compare the algorithms and commonly used software applied to pairwise sequence alignment.The paper can be a reference for researchers to understand the current conditions about sequence alignment and to pick appropriate algorithm and software.关键词
序列比对/两序列比对算法/两序列比对软件/生物信息学Key words
Sequence alignment/Pairwise sequence alignment algorithm/Pairwise sequence alignment software/Bioinformatics分类
信息技术与安全科学引用本文复制引用
焦雅,高静,张文广..两序列比对算法与软件研究进展[J].计算机应用与软件,2015,(6):5-8,13,5.基金项目
国家核高基项目（2010ZX01036－001－001）；内蒙古自然科学基金项目（2010BS0902）；教育部“春晖计划”项目（Z2009－1－01062）；内蒙古自治区科技计划项目“云计算系统安全可靠性的测评技术研究及测试平台构建”。 （）
