实用临床医药杂志Issue(5)：96-98,3.DOI:10.7619/jcmp.201405032
西酞普兰对功能性消化不良患者焦虑、抑郁症状的影响
Influence of citalopram on anxiety and depression of patient with functional dyspepsia
摘要
Abstract
Objective To observe the influence of citalopram on anxiety and depression of patient with functional dyspepsia (FD).Methods One hundred and thirty-two FD patients were randomly divided into treatment group (n =68)and control group (n =64).The patients in con-trol group were given omeprazole and mosapride,while the patients in the treatment group were added citalopram based on the treatment in the control group,and meanwhile given corresponding psychology guidance.The anxiety and depression disorders were evaluated respectively by Self-rat-ing Depression Scale (SDS)and Self-rating Anxiety Scale (SAS).The symptomatic scores before treatment and on the second,fourth and eighth week of treatment,clinical efficiency and adverse reactions were observed in the two groups.Results Among 132 patients,there were 60 with de-pression and 53 patients suffering from anxiety.SDS and SAS scores on on the second,fourth and eighth week of treatment and FD symptomatic scores on the fourth and eighth weeks of treatment were obviously lower,while the overall response rate was significantly higher in treatment group than that in the control group.So the difference was statistical significant.Before and after treat-ment,there were no abnormal patients in two groups.Conclusion FD patients are usually accom-panied by anxiety and depression.The application of citalopram on the basis of routine treatment could significantly ameliorate the patients′anxiety and depression,alleviate symptoms,improve the efficiency and reduce adverse reactions.关键词
西酞普兰/功能性消化不良/情绪障碍/疗效Key words
citalopram/functional dyspepsia/emotional disorder/efficiency分类
医药卫生引用本文复制引用
于开军,李炳东,李国萍,刘晓波,庞素媛..西酞普兰对功能性消化不良患者焦虑、抑郁症状的影响[J].实用临床医药杂志,2014,(5):96-98,3.基金项目
中国高校医学期刊临床专项资金 （）
