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万古霉素微量泵控制持续鞘内注射治疗颅内感染

严建泉 钱东翔 罗鹏 王智坚

实用临床医药杂志Issue(7):91-93,3.
实用临床医药杂志Issue(7):91-93,3.DOI:10.7619/jcmp.201407030

万古霉素微量泵控制持续鞘内注射治疗颅内感染

Microinjection pump control continuous intrathecal injection of vancomycin for the treatment of intracranial infection

严建泉 1钱东翔 1罗鹏 1王智坚1

作者信息

  • 1. 广州医学院第三附属医院 神经外科,广东 广州,510150
  • 折叠

摘要

Abstract

Objective To study the clinical curative effect of continuous intrathecal injec-tion of vancomycin controlled by microinjection pump in the treatment of intracranial infection. Methods 50 patients with intracranial infections from January 2009 to October 2012 were includ-ed in the research.22 patients treated with cerebrospinal fluid drainage from lumbar cistern and discontinuous intrathecal injection of vancomycin were in control group,and another 28 patients with continuous intrathecal injection of vancomycin by micropump were in the experimental group. Therapeutic effect was observed between the two groups.Results The patients in the control group improved more rapidly than those in the experimental group in the temperature,blood,cere-brospinal fluid and other observation index.Compared with the control group,the pain of lower back and leg,convulsions,headache and other side effects were significantly reduced in the experi-mental group.Conclusions Continuous drainage of cerebrospinal fluid in lumbar cistern and mi-croinjection pump control continuous intrathecal injection of vancomycin is a safe and effective method to treat intracranial infection.

关键词

万古霉素/颅内感染/鞘内注射

Key words

vancomycin/intracranial infection/intrathecal injection

分类

医药卫生

引用本文复制引用

严建泉,钱东翔,罗鹏,王智坚..万古霉素微量泵控制持续鞘内注射治疗颅内感染[J].实用临床医药杂志,2014,(7):91-93,3.

实用临床医药杂志

OACSTPCD

1672-2353

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