实用临床医药杂志Issue(13):57-59,3.DOI:10.7619/jcmp.201413018
脱氢表雄酮对卵巢储备低下患者体外受精-胚胎移植的影响
Effect of dehidroepiandroszteron on diminished ovarian reserve patients with in vitro fertilization and embryo transfer
摘要
Abstract
Objective To observe the effect of dehidroepiandroszteron (DHEA)on dimin-ished ovarian reserve (DOR)patients with failed in vitro fertilization and embryo transfer (IVF-ET).Methods A total of 21 patients with ≥1 time of failed IVF-ET were orally administered with 75 mg /d DHEA for 3 months,and IVF-ET was performed again.Relevant indexes in IVF-ET cy-cle before and after oral administration of DHEA were compared.Results DHEA reduced the basic follicle stimulating hormone (FSH)and estradiol (E2)levels,increase basic bilateral antral follicle count (AFC)account,improve relevant indexes in controlled ovarian hyperstimulation (COH)cy-cle,promote pregnant rate in IVF-ET and reduce abortion rate.Conclusion DHEA can effectively improve ovarian response and clinical outcome of IVF-ET for DOR patients.关键词
脱氢表雄酮/卵巢储备功能/体外受精-胚胎移植/妊娠率Key words
dehidroepiandroszteron/diminished ovarian reserve/in vitro fertilization and embryo transfer/pregnant rate分类
医药卫生引用本文复制引用
张平,赵静,王蕴颖,韩晓艳..脱氢表雄酮对卵巢储备低下患者体外受精-胚胎移植的影响[J].实用临床医药杂志,2014,(13):57-59,3.基金项目
中国高校医学期刊临床专项资金项目 ()