实用临床医药杂志Issue(13):113-115,3.DOI:10.7619/jcmp.201413038
紫杉醇联合替吉奥治疗老年进展期胃癌的疗效和安全性
Efficacy and safety of paclitaxel concomitant with Tegafur Gimeracil Oteracil Potassium Capsule in the treatment of patients with advanced gastric carcinoma
摘要
Abstract
Objective To explore the short-term efficacy and toxic and adverse responses of paclitaxel concomitant with Tegafur Gimeracil Oteracil Potassium Capsule in the treatment of pa-tients with advanced gastric carcinoma.Methods Paclitaxel concomitant with Tegafur Gimeracil Oteracil Potassium Capsule were given to 36 elderly patients diagnosed with advanced gastric carci-noma so as to evaluate the clinical efficacy and toxic and adverse responses.Results All patients were available to evaluate the clinical efficacy and toxic and adverse responses,with response rate, disease control rate and medium survival time being 44.4%,80.6% and 9.2 months.The main ad-verse responses were myelosuppression and gastrointestinal responses in degree Ⅰ~Ⅱ.Conclusion Paclitaxel concomitant with Tegafur Gimeracil Oteracil Potassium Capsule have certain efficacy with slight toxic and adverse responses and favorable tolerance,becoming one of the optimal choices in treating elderly patients with advanced gastric carcinoma.关键词
紫杉醇/替吉奥/老年/进展期胃癌Key words
paclitaxel/Tegafur Gimeracil Oteracil Potassium Capsule/elderly patients/advanced gastric carcinoma分类
医药卫生引用本文复制引用
李世栋,吕瑞,金鑫..紫杉醇联合替吉奥治疗老年进展期胃癌的疗效和安全性[J].实用临床医药杂志,2014,(13):113-115,3.基金项目
中国高校医学期刊临床专项资金项目 ()