实用临床医药杂志Issue(15)：32-34,3.DOI:10.7619/jcmp.201415010
上皮细胞黏附分子在食管癌组织中的表达及其临床意义
Clinical significance of epithelial cellular adhesion molecule expression in esophageal carcinoma
摘要
Abstract
Objective To explore the clinical significance of epithelial cellular adhesion molecule (Ep-CAM)expression in esophageal carcinoma.Methods Ep-CAM expression of in 60 cases of esophageal carcinoma、35 cases of atypical hyperplasia and 35 cases of normal esophageal mu-cosa was respectively examined by immunohistochemistry.Results Ep-CAM expression were ob-served with positive in 28.75% of atypical hyperplasia and 90.00% of esophageal carcinoma,but with no positive expression in normal esophageal mucosa.The Ep-CAM expression with positive were significantly differently between degrees of tumor differentiation(P <0.01),lymphatic metas-tasis and 3-year survival(P <0.05).Conclusion The increase of Ep-CAM expression,as a specific index,may has the potential for esophageal cancer diagnosis and prognosis.关键词
上皮细胞黏附分子/食管癌/肿瘤/分化程度/生存期Key words
epithelial cellular adhesion molecule/esophageal carcinoma/tumor/differen-tiation/survival分类
医药卫生引用本文复制引用
张志辉,纪波,穆玉恕..上皮细胞黏附分子在食管癌组织中的表达及其临床意义[J].实用临床医药杂志,2014,(15):32-34,3.基金项目
中国高校医学期刊临床专项资金 （）
