实用临床医药杂志Issue(15)：56-58,3.DOI:10.7619/jcmp.201415017
血管紧张素转化酶抑制剂治疗老年人慢性心力衰竭的有效性与安全性分析
Efficacy and safety analysis of angiotensin converting enzyme inhibitors in the treatment of elderly patients with chronic heart failure
吴秀娟 1张毅1
作者信息
- 1. 陕西省渭南市妇幼保健院，陕西 渭南，714000
- 折叠
摘要
Abstract
Objective To investigate the efficacy and safety of angiotensin converting en-zyme inhibitors(ACEI)in the treatment in elderly patients with chronic heart failure(CHF).Meth-ods 76 elderly patients with CHF were randomly divided into control group and observation group. The control group was treated with diuretic,vasodilator and other conventional anti-heart failure treatment while the observation group was treated with benazepril based on the control group.The echocardiographic indicators and BNP,6min walking distance before and after the treatment were compared in the two groups.Results After treatment,the LVEDD,CO,LVEF ,BNP and 6min walking distance were improved significantly compared with the treatment before in the two groups, and were better in the observation group than that in the control group,the difference was of statis-tically significant (P <0.05).Conclusion The treatment of ACEI in elderly patients with chronic heart failure can significantly improve the heart function,improve exercise tolerance and slow ven-tricular remodeling,so it enjoys a better medication safety.关键词
老年/心力衰竭/心功能/血管紧张素转化酶抑制剂/不良反应Key words
the elderly/heart failure/cardiac function/angiotensin-converting enzyme inhibitors/adverse reactions分类
医药卫生引用本文复制引用
吴秀娟,张毅..血管紧张素转化酶抑制剂治疗老年人慢性心力衰竭的有效性与安全性分析[J].实用临床医药杂志,2014,(15):56-58,3.
