实用临床医药杂志Issue(16)：22-24,3.DOI:10.7619/jcmp.201416006
2型糖尿病并发脑梗死患者联合检测血浆 vWF 水平及血小板参数的临床价值
Clinical value of combined detection of plasma vWF and platelet parameters in patients with type 2 diabetes mellitus complicatedwith cerebral infarction
摘要
Abstract
Objective To explore the clinical significance of plasma vWF and platelet pa-rameters in patients with type 2 diabetes mellitus (T2DM)complicated with cerebral infraction. Methods A total of 32 patients with T2DM complicated with cerebral infraction from December 2011 to October 2013 and another 32 patients with single T2DM were selected as combination group and T2DM group,while another 30 healthy people served as control group.Glycated hemoglobin (HbA1c)level,von Willebrand factor (vWF)level and platelet parameters were detected in 3 groups to observe their differences and the relationship between HbA1c level and vWF level and platelet parameters were analyzed.Results HbA1c and vWF levels decreased gradually in combina-tion and T2DM groups than that in control group,and the differences were significant (P <0.01). There was no significant difference in platelet count (PLT)among 3 groups (P >0.05).However, platelet distribution width (PDW)and mean platelet volume (MPV)decreased evidently and gradu-ally in 3 groups (P <0.01).Additionally,HbA1c level was positive associated with vWF,PMV and PDW (P <0.01).Conclusion Level of vWF increases significantly in patients with T2DM complicated with cerebral infarction,whose detection combined with platelet parametes can provide references for the early diagnosis and treatment.关键词
2 型糖尿病/脑梗死/血管性假性血友病因子/糖化血红蛋白/血小板分布宽度/血小板体积Key words
type 2 diabetes mellitus/cerebral infraction/von Willebrand factor/glcated hemoglobin/platelet distribution width/platelet volume分类
医药卫生引用本文复制引用
鞠晓华,谢宝明,张金彪..2型糖尿病并发脑梗死患者联合检测血浆 vWF 水平及血小板参数的临床价值[J].实用临床医药杂志,2014,(16):22-24,3.基金项目
中国高校医学期刊临床专项资金 （）
