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胰腺癌患者联合检测 CA19-9、CA125、CA242、CEA 的临床意义

艾力江·吐尔逊 张月芬 包永星

实用临床医药杂志Issue(16):33-35,3.
实用临床医药杂志Issue(16):33-35,3.DOI:10.7619/jcmp.201416009

胰腺癌患者联合检测 CA19-9、CA125、CA242、CEA 的临床意义

Clinical significance of combined detection of CA19-9,CA125,CA242 and CEA levels in patients with pancreatic cancer

艾力江·吐尔逊 1张月芬 1包永星1

作者信息

  • 1. 新疆医科大学第一附属医院 肿瘤中心,新疆 乌鲁木齐,830054
  • 折叠

摘要

Abstract

Objective To explore the clinical significance of combined detection of serum carbohydrate antigen 19-9 (CA-19-9),carcinoembryonic antigen (CEA),carbohydrate antigen 125 (CA125)and carbohydrate antigen 242 (CA242)in patients with pancreatic cancer.Methods 65 patients with pancreatic cancer were designed as pancreatic cancer group,another 64 patients with benign pancreatic disease and 66 healthy people with physical examinations at the same period were designed as benign pancreatic disease group and control group respectively.Serum CA19-9,CEA, CA125 and CA242 levels were observed among 3 groups,and the single and combined detection of the sensitivity and specificity of above 4 diagnostic indexes in detecting pancreatic cancer were con-ducted.Results Serum CA19-9,CEA,CA125 and CA242 levels were significantly higher in pan-creatic cancer group than the other two groups (P <0.01),and the sensitivity and specificity of combined detection of above 4 indexes were 87.69% and 91.54% respectively.Conclusion Serum CA19-9,CEA,CA125 and CA242 levels increase significantly in patients with pancreatic cancer, and their combined detection has a higher diagnostic value.

关键词

胰腺癌/肿瘤标志物/糖抗原 19-9/癌胚抗原/糖抗原 125/糖抗原 242/胰腺炎

Key words

pancreatic cancer/tumor marker/carbohydrate antigen 19-9/carcinoembry-onic antigen/carbohydrate antigen 125/carbohydrate antigen 242/pancreatitis

分类

医药卫生

引用本文复制引用

艾力江·吐尔逊,张月芬,包永星..胰腺癌患者联合检测 CA19-9、CA125、CA242、CEA 的临床意义[J].实用临床医药杂志,2014,(16):33-35,3.

基金项目

中国高校医学期刊临床专项资金 ()

实用临床医药杂志

OACSTPCD

1672-2353

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