实用临床医药杂志Issue(17)：8-11,4.DOI:10.7619/jcmp.201417003
低分子肝素钙对肺源性心脏病心力衰竭患者临床疗效及血浆N-末端脑钠肽前体、D-二聚体水平的影响
Clinical effects of low molecular heparin calcium on N-terminal pro-brain natriuretic peptide and blood plasma D-dipolymer level in heart failure patients with pulmonary heart disease
摘要
Abstract
Obj ective To observe the clinical effects of low molecular heparin calcium on hemorheology,N-terminal pro-brain natriuretic peptide (NT-proBNP)and blood plasma D-dipoly-mer (D-D)level in heart failure patients with pulmonary heart disease.Methods 95 heart failure patients with pulmonary heart disease were randomly divided into observation (n= 45 )and control groups (n= 50),both treated with regular treatment.Extra hypodermic injection of low molecular heparin calcium was given to observation group.Clinical effects,adverse events,hemorheology,N-terminal pro-brain natriuretic peptide (NT-proBNP)and blood plasma D-dipolymer (D-D)level were observed.Results Effective rate in observation group (95 .56%)was significantly higher than in control group (82.00%)(P<0.05),and significant difference was found in adverse events. Hemorheology,N-terminal pro-brain natriuretic peptide (NT-proBNP)and blood plasma D-dipoly-mer (D-D)level were improved in both groups after treatment (P<0.05,P<0.01),and differ-ences between 2 groups were significant (P<0.05,P<0.01).Conclusion Low molecular hep-arin calcium combined with dobutamine and magnesium sulfate has the potential to improve the hemorheology,N-terminal pro-brain natriuretic peptide (NT-proBNP)and blood plasma D-dipoly-mer (D-D)level in heart failure patients with pulmonary heart disease.关键词
肺源性心脏病/心力衰竭/低分子肝素钙/血液流变学/N-末端脑钠肽前体/D-二聚体/血栓Key words
pulmonary heart disease/heart failure/low molecular heparin calcium/hemorheology/N-terminal pro-brain natriuretic peptide/blood plasma D-dipolymey/thrombus分类
医药卫生引用本文复制引用
奚正荣,胡鑫,刘文兵..低分子肝素钙对肺源性心脏病心力衰竭患者临床疗效及血浆N-末端脑钠肽前体、D-二聚体水平的影响[J].实用临床医药杂志,2014,(17):8-11,4.基金项目
中国高校医学期刊临床专项资金 （）
