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急性缺氧对健康人三尖瓣返流的影响

李双菲 武晓静 杨特 李相俊 覃军 刘曦 黄岚

军事医学Issue(4):245-247,251,4.
军事医学Issue(4):245-247,251,4.DOI:10.7644/j.issn.1674-9960.2014.04.002

急性缺氧对健康人三尖瓣返流的影响

Effect of acute hypoxia on tricuspid regurgitation

李双菲 1武晓静 1杨特 1李相俊 1覃军 1刘曦 1黄岚1

作者信息

  • 1. 第三军医大学新桥医院,全军心血管病研究所,重庆400037
  • 折叠

摘要

Abstract

Objective To explore the effect of acute hypoxia on tricuspid regurgitation .Methods 176 healthy young males were selected and their tricuspid regurgitation parameters in normoxia and after acute exposure to hypoxia ( oxygen concentrations 12%) were collected by color Doppler technology .The conditions of tricuspid regurgitation were compared between the two groups .Results Tricuspid regurgitation was significantly increased after the subjects were exposed to hypoxia.Tricuspid regurgitation rate (76% vs 48%), regurgitation pressure (25.65 mmHg vs 19.33 mmHg) and maxi-mum regurgitation velocity (251.38 cm/s vs 220.62 cm/s) were higher in the hypoxia group .However, there was no significant change in the regurgitation area .After two weeks of adaptation to hypoxia , the tricuspid regurgitation rate (50%vs 76%), regurgitation pressure (20.83 mmHg vs 25.65 mmHg) and maximum regurgitation velocity (225.69 cm/s vs 251.38 cm/s) significantly decreased and returned to the level before hypoxic exposure .Conclusion Acute hypoxic expo-sure can induce and aggravate tricuspid regurgitation ,and short-term adaptation to hypoxia can reverse the trend .

关键词

三尖瓣返流/缺氧/高原

Key words

tricuspid regurgitation/hypoxia/high altitude

分类

医药卫生

引用本文复制引用

李双菲,武晓静,杨特,李相俊,覃军,刘曦,黄岚..急性缺氧对健康人三尖瓣返流的影响[J].军事医学,2014,(4):245-247,251,4.

基金项目

国家卫计委卫生行业科研专项基金资助项目(201002012);国家自然科学基金资助项目 ()

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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