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基于CYP2 C9靶蛋白的心血管药物个体化用药效能评价

童跃锋 杨帅 胡智星 王云乡 赖长春 李浙成 苏琴

军事医学Issue(4):294-297,4.
军事医学Issue(4):294-297,4.DOI:10.7644/j.issn.1674-9960.2014.04.015

基于CYP2 C9靶蛋白的心血管药物个体化用药效能评价

Effectiveness evaluation of personalized medication for cardiovascular drugs based on the CYP2 C9 protein

童跃锋 1杨帅 2胡智星 1王云乡 1赖长春 1李浙成 1苏琴3

作者信息

  • 1. 浙江省永康市第一人民医院,浙江永康 321300
  • 2. 军事医学科学院放射与辐射医学研究所,北京 100850
  • 3. 解放军总医院第一附属医院,北京 100048
  • 折叠

摘要

Abstract

Objective To analyze the effectiveness evaluation of cardiovascular drugs which have been developed on the CYP2C9 target protein by multi-layer fuzzy evaluation technology .Methods The multi-layer fuzzy evaluation method was used to evaluate the effectiveness of cardiovascular drugs interacting with the CYP 2C9 protein and to construct the index system that affects drug efficacy .Results and Conclusion The index system was used to study such cardiovascular drugs as valsartan and to score the drug effectiveness of individual samples .The results were consistent with actual drug treatment and were well confirmed .The results contribute to evaluation of personalized medication .

关键词

CYP2 C9/心血管药物/效能评价/多层次模糊评价

Key words

CYP2C9/cardiovascular drugs/effectiveness evaluation/multi-layer fuzzy evaluation

分类

医药卫生

引用本文复制引用

童跃锋,杨帅,胡智星,王云乡,赖长春,李浙成,苏琴..基于CYP2 C9靶蛋白的心血管药物个体化用药效能评价[J].军事医学,2014,(4):294-297,4.

基金项目

浙江省科技厅面上科技资助项目 ()

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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