军事医学Issue(7)：514-517,522,5.DOI:10.7644/j.issn.1674-9960.2014.07.011
常见高致病性病原微生物环境安全临界值研究
Environmental safety threshold of commonly encountered highly pathogenic microor-ganisms
摘要
Abstract
Objective To study environmental safety reference standard values of commonly encountered pathogenic microorganisms, and provide the basis for environmental risk assessment of a high-level biosafety laboratory (BSL).Methods Using human exposure dose calculation methods as the basic principle in combination with microbial hazard evaluation methods , an infectious dose calculation model of human exposure to pathogenic microorganisms by breathing was proposed . Based on research on characteristics of commonly encountered pathogenic microorganisms at home and abroad , the environ-mental safety threshold reference standard and environmental risk protection zone for such microorganisms were obtained . Results An the environmental risk assessment standard calculation method for commonly encountered highly pathogenic microorganisms was proposed , and the minimum infectious dose and environmental safety threshold of seven commonly encountered pathogenic microorganisms were obtained , including SARS coronavirus , highly pathogenic avian influenza virus, Mycobacterium tuberculosis, Bacillus anthracis, Yersinia pestis,Francisella tularensis, and epidemic hemorrhagic fever virus.Conclusion The results can be used as a reference standard of infectious aerosols in a high-level BSL for environ-mental risk assessment , laboratory risk control and emergency management .关键词
病原微生物/安全临界值/防护距离/暴露剂量/环境风险Key words
pathogenic microorganisms/safety threshold/protection zone/exposure dose/environmental risk分类
医药卫生引用本文复制引用
丁峰,李时蓓,温占波,胡翠娟..常见高致病性病原微生物环境安全临界值研究[J].军事医学,2014,(7):514-517,522,5.基金项目
国家环境保护部环保公益性行业科研专项资助 （）
