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炭疽芽孢杆菌芽孢萌发研究进展

高志奇 刘先凯 王恒樑

军事医学Issue(10):833-836,4.
军事医学Issue(10):833-836,4.DOI:10.7644/j.issn.1674-9960.2014.10.022

炭疽芽孢杆菌芽孢萌发研究进展

Germination of Bacillus anthracis spores:research advances

高志奇 1刘先凯 1王恒樑1

作者信息

  • 1. 军事医学科学院生物工程研究所病原微生物生物安全国家重点实验室,北京 100071
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摘要

Abstract

A spore is another life cycle form of Bacillus anthracis for resisting starvation.When conditions are favorable for growth, the dormant spore will germinate,go through outgrowth, and are ultimately converted back into a growing cell. As the first step back to vegetative growth, germination could be induced by nutrients and a variety of non-nutrient agents. Nutrient germinants trigger cation release and water absorption by binding to receptors in the spore′s inner membrane.Then the spore′s peptidoglycan cortex is hydrolyzed and the spore core rehydrates, which allows the resumption of spore metabo-lism and macromolecular synthesis.This paper reviews the nutrient germinant receptor and cortex lytic enzymes in the spore germination process of B.anthracis.

关键词

芽孢杆菌,炭疽/芽孢萌发/萌发受体/萌发通路

Key words

Bacillus anthracis/spore germination/germinant receptor/germinant pathway

分类

医药卫生

引用本文复制引用

高志奇,刘先凯,王恒樑..炭疽芽孢杆菌芽孢萌发研究进展[J].军事医学,2014,(10):833-836,4.

基金项目

国家自然科学基金资助项目 ()

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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