解放军医学院学报Issue(4)：305-308,317,5.DOI:10.3969/j.issn.2095-5227.2015.04.002
评价房颤CHADS2评分及其衍生评分对冠心病及其严重程度的预测价值
Prediction of coronary artery disease severity using CHADS2, CHA2DS2-VASc and CHA2DS2-VASc-HSF scores
摘要
Abstract
Objective To determine the value of CHADS2, CHA2DS2-VASc and CHA2DS2-VASc-HSF scores for prediction of CAD severity.Methods Clinical data about 429 patients who underwent coronary angiography in the department of cardiology in Chinese PLA General Hospital from January 2013 to December 2013 were collected. These patients were divided into control group (n=51) and CAD group (n=378) based on the result of CAG. According to the clinical data, CHADS2, CHA2DS2-VASc and CHA2DS2-VASc-HSF scores were respectively calculated. Furthermore, AUC were calculated to access the predictive ability of three kinds of scores.ResultsThe CHADS2, CHA2DS2-VASc and CHA2DS2-VASc-HSF scores were correlated with the number of diseased vessels (r=0.317,P<0.01;r=0.332,P<0.01;r=0.330,P<0.01, respectively) and the Gensini score (r=0.240,P<0.01;r=0.274, P<0.01;r=0.295,P<0.01, respectively). For prediction of CAD, the cut-off value of CHA2DS2-VASc-HSF score was≥3 with a sensitivity of 86.0% and a specificity of 80.4% (AUC 0.832, 95%CI 0.766 to 0.898,P<0.001).Conclusion CHADS2, CHA2DS2-VASc and especially CHA2DS2-VASc-HSF score can predict the individual risk of developing CAD.关键词
冠心病/CHADS2评分/CHA2DS2-VASc评分Key words
coronary disease/CHADS2 score/CHA2DS2-VASc score分类
医药卫生引用本文复制引用
李月蕊,刘洋,张辉,刘宏斌..评价房颤CHADS2评分及其衍生评分对冠心病及其严重程度的预测价值[J].解放军医学院学报,2015,(4):305-308,317,5.基金项目
全军医药卫生科研基金(11BJZ19) Supported by the Military Medical and Health Research Foundation(11BJ Z19) （11BJZ19）
