解放军医学院学报2015，Vol.36Issue(6)：532-535,4.DOI:10.3969/j.issn.2095-5227.2015.06.003
29例非中性粒细胞缺乏患者侵袭性肺曲霉病临床分析
Invasive pulmonary aspergillosis in non-neutropenic patients: A clinical analysis of 29 cases
摘要
Abstract
Objective To investigate the clinical characteristics of invasive pulmonary aspergillosis (IPA) in non-neutropenic patients. Methods Clinical and imaging characteristics about 29 patients with proven and probable IPA admitted to department of respiratory diseases from January 2011 to December 2013 were retrospectively analyzed.Results Patients were classified into proven IPA group (n=12) and probable IPA group (n=17). The mostcommon underlying disease of patients with IPA was chronic respiratory disease (n=11), diabetes mellitus and no basic diseases, each occurred in 7 cases. The average time from onset to diagnosis was 16.5 days. Clinical symptoms were nonspecific in non-neutropenic patients with IPA. The most common chest CT scanfindings of patients with IPA were infiltrates.Conclusion IPA should be taken into account in the differential diagnosis particularly in non-neutropenic patients with dyspnea, cough, sputum, PCT normal values and a new pulmonary infiltrate that are irresponsive to broad-spectrum antibiotics and steroids.关键词
非中性粒细胞缺乏/侵袭性肺曲霉病/临床分析Key words
non-neutropenic/invasive pulmonary aspergillosis/clinical analysis分类
医药卫生引用本文复制引用
蔡学究,倪文涛,魏传琦,崔俊昌..29例非中性粒细胞缺乏患者侵袭性肺曲霉病临床分析[J].解放军医学院学报,2015,36(6):532-535,4.基金项目
国家自然科学基金项目(81371855) Supported by the National Natural Science Foundation of China(81371855) （81371855）
