解放军医学院学报2015，Vol.36Issue(6)：553-555,558,4.DOI:10.3969/j.issn.2095-5227.2015.06.008
腹膜后多形型脂肪肉瘤的外科治疗及预后影响因素分析
Surgical therapy and prognostic factors analysis of retroperitoneal pleomorphic liposarcoma
孙成博 1李沛雨 1卢灿荣 1黄晓辉 1张楠 1刘娜1
作者信息
- 1. 解放军总医院 普通外科,北京 100853
- 折叠
摘要
Abstract
Objective To evaluate the treatment outcome and identify prognostic factors for patients with retroperitoneal pleomorphic liposarcoma.Methods Clinical data about 47 patients with retroperitoneal pleomorphic liposarcoma managed with surgery from June 2007 to December 2013 in our hospital were retrospectively analyzed and all patients were followed up.Results Of the 47 cases, 17 patients received surgicalresection for thefirst time, 30 patients were recurrent, 35 patients received radical resection, 12 cases received partial resection. The overall 1-, 3-, 5-year survival were 86.9%, 52.5% and 32.0% and the median survival time was 20 (2- 64) months. Log Rank test showed that radical surgery (χ2=43.038,P<0.01) and tumor necrosis (χ2=7.280,P=0.007) were associated with postoperative survival time. The difference between gender, age, removal of the joint organs, tumor size, primary or recurrent showed no statistical significance. Multivariate analysis showed that radical surgery (RR=61.630,P<0.01) and tumor necrosis (RR=0.216,P=0.019) were prognostic indicators for retroperitoneal pleomorphic liposarcoma.Conclusion Retroperitoneal pleomorphic liposarcoma is the rarest type. It belongs to the high grade of tumor, and its prognosis is poor. Complete resection remains the mainstream treatment for retroperitoneal pleomorphic liposarcoma. In order to reach the goal of radical resection, resections of other adjacent organs are often needed. Radical resection and no tumor necrosis predict better postoperative survival period.关键词
多形型脂肪肉瘤/腹膜后肿瘤/手术治疗/预后Key words
pleomorphic liposarcoma/retroperitoneal neoplasms/surgery/prognosis分类
医药卫生引用本文复制引用
孙成博,李沛雨,卢灿荣,黄晓辉,张楠,刘娜..腹膜后多形型脂肪肉瘤的外科治疗及预后影响因素分析[J].解放军医学院学报,2015,36(6):553-555,558,4.
