解放军医学院学报Issue(7)：699-701,723,4.DOI:10.3969/j.issn.2095-5227.2015.07.016
颅内多发高级别胶质瘤手术治疗及预后分析
Surgical treatment of patients with intracranial multiple high grade glioma and its prognosis
余鹏霄 1马晓东 1张猛 1王强 1徐维林 1张宏伟1
作者信息
- 1. 解放军总医院 神经外科，北京 100853
- 折叠
摘要
Abstract
Objective To explore the effects of operative and non-operative treatment for the intracranial high-grade multiple glioma. Methods Clinical characteristics, operative treatment and follow-up results in patients with high-grade multiple glioma that were confirmed by images and postoperative pathology from January 2008 to November 2013 in Chinese PLA General Hospital were retrospectively analyzed. Patients were divided into operative treatment group (n=27) and non-operative treatment group (n=10). The survival of patients in operative and non-operative treatment were compared. In operative treatment group, there were 15 males and 12 females with a mean age of (44.4±13.6) years (range, 8-67 years) and their mean KPS score were (73.5±10.1) (range, 50-90). Of the 27 cases, WHOⅣwas found in 21 cases and WHOⅢin 6 cases. In non-operative treatment group, there were 4 males and 6 females with a mean age of (47.3±14.9) years (range, 20-71 years) and their mean KPS score were (75.5±11.3) (range, 50-90). Of the 10 cases, WHOⅣwas found in 7 cases and WHOⅢin 3 cases. Results The gross total resection, subtotal resection and partial resection rates were 11.1%, 18.5%and 70.4%. 19 cases were auxiliary to radiation or chemotherapy in operative treatment group, and 8 cases in non-operative treatment group. Patients were followed up for 1-24 months. The survival rate of 6-month, 1-year of operative treatment group and non-operative treatment group were 77.8%, 32.1%and 35.0%, 11.7%. The median survival time of operative treatment group was 10.0 months, which was longer than that of non-operative treatment group (5.5 months). Conclusion Compared with non-operative treatment, surgical removal of the tumor can prolong the survival time in treatment of intracranial multiple high-grade glioma.关键词
多发胶质瘤/高级别胶质瘤/手术治疗Key words
multiple glioma/high-grade glioma/operation分类
医药卫生引用本文复制引用
余鹏霄,马晓东,张猛,王强,徐维林,张宏伟..颅内多发高级别胶质瘤手术治疗及预后分析[J].解放军医学院学报,2015,(7):699-701,723,4.
