教育生物学杂志Issue(3)：174-179,6.DOI:10.3969/j.issn.2095-4301.2014.03.006
益生菌对儿童与青少年功能性便秘治疗效果的Meta分析
Efficacy of probiotic supplementation for treatment of functional constipation in children and adolescents：Meta-analysis
王俊丽 1陈涛 1李锋 1盛晓阳 1薛敏波1
作者信息
- 1. 上海交通大学医学院附属新华医院儿童与青少年保健科 中国上海 200092
- 折叠
摘要
Abstract
Objective To assess the efficacy of probiotic supplementation for treatment of functional constipation in children and adolescents, and provide evidence for clinical practice. Methods Relevant randomized controlled trials were collected by electronic searching for domestic and overseas literature. Revman 5.1 software was adopted for statistical analy sis and description of outcome parameters. Results Six randomized controlled trials were included. Meta-analysis revealed that probiotic supplementation had no significant therapeutic effect in overall participants with functional constipa-tion. Subgroup analysis demonstrated that probiotic supplementation did not significantly ameliorate symptoms (abdominal pain, stool frequency, stool hardness and fecal soiling) of participants with functional constipation. Conclusion Meta-analysis indicates that probiotic supplementation may not have therapeutic effect on functional constipation in children and adolescents.关键词
功能性便秘/儿童与青少年/益生菌/Meta分析Key words
functional constipation/child and adolescent/probiotic/Meta-analysis引用本文复制引用
王俊丽,陈涛,李锋,盛晓阳,薛敏波..益生菌对儿童与青少年功能性便秘治疗效果的Meta分析[J].教育生物学杂志,2014,(3):174-179,6.
