检验医学与临床Issue(12)：1657-1659,3.DOI:10.3969/j.issn.1672-9455.2014.12.029
阴道病原菌感染与胎膜早破的关系及其耐药性分析
Infectious characteristic analysis and drug-resistance of pathogens among vagina infection pregnancy with premature rup-ture of membranes
摘要
Abstract
Objective The distribution characteristics and antibiotic resistance of specific pathogens among va-gina infection pregnancy with premature rupture of membranes (prom) ,in order to guide rational antibacterial thera-py .Methods During the periods of Jan ,2010 to Jul ,2012 ,pathogens from vagina with infectious pregnancy were gathered ,two groups-prom group and normal control were divided .The drug sensitivity of isolated strains were deter-mined by the broth dilution method .Results Only Streptococcus agalactiae (b group) and Staphylococcus aureus were found statistical significance between the two groups ,presenting higher detection in prom group(P<0 .05) .The resistant rates of Staphylococcus aureus to penicillin and ampicillin were 100% ,the sensitivity rates to erythrocin and azithromycin were 33 .3% and 50% ,respectively ,to tetracycline were 66 .7% ,others were all above of 83 .3% .The sensitivity rates of Streptococcus agalactiae (b group) to levofloxacin ,azithromycin ,erythrocin ,and ofloxacin were 30% ~40% ,yet above 80% of sensitivity to penicillin and cephems .Conclusion Streptococcus agalactiae (b group) and Staphylococcus aureus have an effect on prom .The drug sensitivity to the two bacteria are effected .Rational use of antibiotics and surveillance should be taken into account ,to avoid the development of drug-resistance strains .关键词
胎膜早破/阴道分泌物/孕妇/病原菌/耐药性Key words
premature rupture of membranes/vaginal fluid/pregnancy/pathogens/drug-resistance引用本文复制引用
楚丽娟,罗婷婷,杨桂林,李秋红..阴道病原菌感染与胎膜早破的关系及其耐药性分析[J].检验医学与临床,2014,(12):1657-1659,3.基金项目
重庆市卫生局课题（2013-2-133）。 （）
