检验医学与临床Issue(13)：1781-1782,2.DOI:10.3969/j.issn.1672-9455.2014.13.016
实验室评价抗dsDNA抗体检测试剂盒优劣的方法
Evaluation of different kits for the detection of anti-dsDNA antibody
摘要
Abstract
Objective To evaluate the performance of two different kit for the detection of anti‐dsDNA anti‐body .Methods A total of 50 patients with definite diagnosis of systemic lupus erythematosus (SLE) was enrolled as experiment group from Jun .2013 to Oct .2013 ,and 50 cases of healthy subjects were enrolled as control group .Serum samples were collected ,and detected for anti‐dsDNA antibody by kits of Sichuan Xincheng Biotechnology Ltd .Com‐pany (kits A ) and kits of another manufacture (kits B) ,and the results were statistically analyzed .Results The positive coincidence rate of kits A for the detection of samples of experiment group was 88 .0% ,higher than the 82 .0% of kits B .The negative coincidence rates of the two kits for the detection of samples of control group were at the same level .Concordance analysis indicated that the Kappa values of kits A and kits B were 0 .84 and 0 .78 respec‐tively .Conclusion There could be equivalence of the kits A and kits B for the detection of anti‐dsDNA antibody ,and the former might be with higher clinical coincidence rate .关键词
抗dsDNA抗体/系统性红斑狼疮/线性免疫分析法Key words
anti-dsDNA antibody/systemic lupus erythematosus/linear immune analysis引用本文复制引用
曹珂,刘会彩..实验室评价抗dsDNA抗体检测试剂盒优劣的方法[J].检验医学与临床,2014,(13):1781-1782,2.
