检验医学与临床Issue(14)：1893-1894,1897,3.DOI:10.3969/j.issn.1672-9455.2014.14.002
乙型病毒性肝炎血清流行病学调查及病毒基因型研究
Epidemiological investigation of viral hepatitis type B and viral genotypes
摘要
Abstract
Objective To investigate the prevalence of the viral hepatitis type B and viral genotypes in Dong-guan area .Methods Centralized collection and home collection were performed for questionnaire survey and blood samples detection in 1 041 subjects of Dongguan area in groups of different ages .Results The infectious rage of hep-atitis B virus (HBV) was 30 .5% (318/1 041) ,including of 72 .0% (229/318) of genotype B ,24 .8% (79/318) of gen-otype C ,1 .6% (5/318) of genotype D ,and 1 .6% (5/318) of mixed genotypes B and C .In different subtypes of B gen-otype ,Ba subtype accounted for 91 .0% and adw2 serotype accounted for 93 .6% .In different subtpes of C genotype , C2 subtype accounted for 92 .0% and adrq+ serotype accounted for 85 .0% .Patients with chronic hepatitis B was given priority to type B gene in Dongguan ,followed by type C gene .Conclusion The prevalence of hepatitis type B might be with age and area difference in Dongguan area .Further study of HBV genotypes and prevalence status might be helpful for developing strategies to prevent and treatment of hepatitis type B .关键词
乙型病毒性肝炎/流行现状/病毒基因型/乙型肝炎病毒Key words
viral hepatitis type B/epidemic situation/virus genotype/hepatitis B virus引用本文复制引用
胡忠金,李英姿,邓小够,邓周,邱跃华..乙型病毒性肝炎血清流行病学调查及病毒基因型研究[J].检验医学与临床,2014,(14):1893-1894,1897,3.基金项目
广东省东莞市科技局计划项目（201210515000167）。 （）
