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3项生化指标在诊断小儿病毒性心肌炎中的临床意义

颜海青 杨冰

检验医学与临床Issue(14):1916-1917,1920,3.
检验医学与临床Issue(14):1916-1917,1920,3.DOI:10.3969/j.issn.1672-9455.2014.14.012

3项生化指标在诊断小儿病毒性心肌炎中的临床意义

Clinical significance of NT-proBNP,cTnI and CK-MB in the diagnosis of viral myocarditis in children

颜海青 1杨冰1

作者信息

  • 1. 广东省广州市越秀区儿童医院 510115
  • 折叠

摘要

Abstract

Objective To explore the clinical significance of N-terminal pro-brain nitric peptide (NT-proB-NP) ,cardiac troponin I (cTnI) and isoenzyme of creatinkinase (CK-MB) in the diagnosis of viral myocarditis (VMC) in children with main symptoms of abdominal pain .Methods A total of 7 children with VMC and abdominal (VMC group) ,33 children without VMC but with symptoms of abdominal pain and unstable blood circulation (non-VMC group) ,and 40 healthy children (control group) were enrolled and detected for serum levels of NT-proBNP ,cTnI and CK-MB .Results Serum levels of NT-proBNP ,cTnI and CK-MB in VMC group were higher than non-VMC group and control group (P<0 .01) .Serum level of CK-MB in non-VMc group was higher than control group (P<0 .01) . The sensitivity and specificity of NT-proBNP for the diagnosis of VMC were 100 .0% and 90 .90% ,of cTnI were 71 .40% and 84 .80% ,and of CK-MB were 57 .14% and 39 .40% .Conclusion Serum NT-proBNP ,cTnI and CK-MB might be sensitive indicators for the diagnosis of VMC in children with main symptoms of abdominal pain .

关键词

病毒性心肌炎/腹痛/氨基末端脑利钠肽前体/心肌肌钙蛋白I/肌酸激酶同工酶

Key words

viral myocarditis/abdominal pain/N-terminal pro-brain nitric peptide/cardiac troponin I/creatine rinase isoenzyme

引用本文复制引用

颜海青,杨冰..3项生化指标在诊断小儿病毒性心肌炎中的临床意义[J].检验医学与临床,2014,(14):1916-1917,1920,3.

检验医学与临床

OACSTPCD

1672-9455

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