摘要
Abstract
Objective To study the expression of serum NSE (neuron specific enolase) and ET (endothelin) and S100B protein in patients with ACI (caute cerebral infarction ,and get the relation between the degree of neural function defect in the acute stage .Methods Retrospective analysis of our hospital from 2008 May to 2012 May ,clini-cal data of 90 patients with ACI treated in our department (observation group) ,and the same period of treatment of 62 cases of non nervous system disease in patients with clinical data (control group) ,comparative analysis of NSE and ET of two groups of nerve function defect degree ,serum ,and the expression of S100B protein .Results Observation of NSE and ET in serum ,and the expression of S100B protein compared with control group ,both groups were in-creased in different degree ,difference was significant(P < 0 .01);to observe the degree of neural function defect pa-tients ,with serum NSE and ET ,and the expression of S100B protein ,showed significant difference(P<0 .01) .Con-clusion NSE and ET in the sera of ACI patients ,and the expression of S100B protein ,has a close relationship with the degree of neural function defect ,the defect degree of the nervous function more weight ,NSE and ET in serum , and the content of S100B protein is higher ,so the three indicators can be a sensitive marker for brain damage in ACI patients ;it can be used to judge the patient′s condition ,evaluate the prognosis ,and is very suitable for those can not be imaging diagnosis of ACI patients .关键词
急性脑梗死/内皮素/S100B蛋白/神经元特异性烯醇化酶/神经功能缺损Key words
acute cerebral infarction/endothelin/S100B protein/neuron specific enolase/neural func-tion defect
