检验医学与临床Issue(16)：2244-2245,2248,3.DOI:10.3969/j.issn.1672-9455.2014.16.022
尼莫地平与硫酸镁治疗蛛网膜下腔出血后脑血管痉挛的随机对照研究
Randomized controlled study comparing effect of nimodipine with magnesium sulfate on cerebral vasospasm after sub-arachnoid hemorrhage
田宇1
作者信息
- 1. 湖北省黄冈市中心医院神经内科 438000
- 折叠
摘要
Abstract
Objective To compare the effect of cerebral vasospasm after subarachnoid hemorrhage treated by nimodipine and magnesium sulfate .Methods 61 patients with cerebral vasospasm after subarachnoid hemorrhage were divided into nimodipine group(31 cases) and magnesium sulfate group(30 cases) ,patients in nimodipine group received the treatment of nimodipine ,while others received the treatment of magnesium sulfate .Results The Vp of left and right ACA ,left and right MCA in magnesium sulfate group which were (81 .2 ± 9 .1) ,(80 .8 ± 12 .2) , (122 .6 ± 20 .7) and(118 .4 ± 21 .6)cm/s were significantly higher than that of nimodipine group which were (70 .6 ± 10 .2) ,(68 .6 ± 10 .7) ,(100 .5 ± 16 .6) and(101 .5 ± 12 .7)cm/s(P<0 .05) .The meningeal stimulation response rate of nimodipine group was 77 .4% ,which was significantly higher than that of magnesium sulfate group which was 50 .0% (P< 0 .05) .The incidence of complications were also compared between the two groups ,the rate of blood pressure drop in nimodipine group was significantly higher than that in magnesium sulfate group (P<0 .05) .Conclu-sion Nimodipine has significantly therapeutic effect in treatment of CVS caused by SA H ,and its curative effect is better than magnesium sulfate .nimodipine has good safety and easy use .It is worthy of clinical promotion and further study .关键词
蛛网膜下腔出血/脑血管痉挛/尼莫地平/硫酸镁Key words
subarachnoid hemorrhage/cerebral vasospasm/nimodipine/magnesium sulfate引用本文复制引用
田宇..尼莫地平与硫酸镁治疗蛛网膜下腔出血后脑血管痉挛的随机对照研究[J].检验医学与临床,2014,(16):2244-2245,2248,3.
