检验医学与临床Issue(20)：2882-2883,2.DOI:10.3969/j.issn.1672-9455.2014.20.036
N-末端脑钠肽前体与心肌坏死标志物在慢性心力衰竭患者中的检测意义
Value of N-terminal probrain natriuretic peptide and myocardial necrosis markers in patients with chronic heart failure
摘要
Abstract
Objective To explore the levels of N-terminal probrain natriuretic peptide (NT-proBNP) ,cardiac troponin I2 (cTnI2) ,myoglobin (MYO) and creatin kinase myocardial type MB (CK-MB) in patients with chronic heart failure (CHF) .Methods A total of 209 patients with CHF from Jun .2009 to Jun .2012 were selected into CHF group ,60 healthy people were selected as control group .Patients were divided into four groups based on the heart function classification assay of American heart association (NYHA ) .The levels of NT-proBNP ,cTnI2 ,MYO and CK-MB were detected and compared in the two groups .Results The level of NT-proBNP in the CHF group was sig-nificant higher than that of the control group(P < 0 .05) .There were significant differences on the level of NT-proB-NP in four heart function classification groups (P< 0 .05) .The levels of cTnI2 ,MYO ,and CK-MB in four heart func-tion classification groups increased as the disease developed ,but the differences were still lower than the level of NT-proBNP .Conclusion The level of NT-proBNP in patients with CHF could predict the progress of this disease .关键词
慢性心力衰竭/N-末端脑钠肽前体/心肌肌钙蛋白/肌红蛋白/肌酸激酶同工酶Key words
Chronic heart failure/N-terminal probrain natriuretic peptide/cardiac troponin I2/myoglo-bin/creatin kinase myocardial type MB引用本文复制引用
尚宝荣..N-末端脑钠肽前体与心肌坏死标志物在慢性心力衰竭患者中的检测意义[J].检验医学与临床,2014,(20):2882-2883,2.
