检验医学与临床Issue(22)：3092-3093,3096,3.DOI:10.3969/j.issn.1672-9455.2014.22.002
免疫固定电泳对多发性骨髓瘤的诊断价值
Diagnostic value of immunofixation electrophoresis on multiple myeloma
摘要
Abstract
Objective To evaluate the value of immunofixation electrophoresis(IFE)in the diagnosis of multiple myeloma(MM) .Methods The Sebia Hydrasys 2 agarose electrophoresis apparatus made byFrance was adopted to perform IFE on the serum samples in the patients with the clinical IFE detection demand .The related laboratory detection data of these patients were retrospectively analyzed .Results Among 155 cases of IFE detection results ,67 cases were positive ,in which 51 cases of MM were verified by clinical diagnosis .The sensitivity and specificity of IFE for diagnosing MM were 69 .9% and 80 .5% respectively .In 51 cases of MM ,IgG kappa type and IgG lambda type were predominant ,accounting for 19 .61% and 27 .45% ,respectively ,but the other types had distribution .The retrospective analysis results of the medical record data in 51 cases of MM and positive IFE showed that the patients often visited to other departments because the primary disease was covered with the initial symptoms such as anemia ,bone pain .Conclusion IFE has important clinical significance for accurately diagnosing MM ,monitoring the curative effect and judging prognosis .关键词
多发性骨髓瘤/免疫固定电泳/M蛋白Key words
multiple myeloma/immunofixation electrophoresis/M protein引用本文复制引用
廖君群,杨清秀,毕小云..免疫固定电泳对多发性骨髓瘤的诊断价值[J].检验医学与临床,2014,(22):3092-3093,3096,3.基金项目
国家临床重点专科建设项目（财社［2010］305号）。 （）
