检验医学与临床Issue(22)：3112-3113,2.DOI:10.3969/j.issn.1672-9455.2014.22.010
N末端脑钠肽前体水平对预测窒息新生儿心肌损害的价值探讨
Value of NT-proBNP level for predicting myocardial damage in asphyxia neonates
苑文雯 1王晗 1耿伟 1何叶莉 1朱剑功 1李沛然 1杨宁 1李妍 1郭桐生1
作者信息
- 1. 解放军第三〇二医院 临床检验医学中心，北京 100039
- 折叠
摘要
Abstract
Objective To investigate the predictive value of plasma N‐terminal brain natriuretic peptide(NT‐proBNP)level on myocardial damage in neonatal asphyxia .Methods 36 neonates with asphyxia in our hospital were selected as the observation group ,including 23 cases of mild asphyxia and 13 cases of severe asphyxia;at the same time 36 healthy neonates during the same period in this hospital were selected as the control group .The plasma crea‐tine kinase MB(CK‐MB) ,myoglobin(Mb)and troponin T (TnT )levels in venous blood specimens within 72 h after birth from these enrolled neonates were measured ,and the NT‐proBNP level was simultaneously determined .The de‐tection results were performed the comparative anaysis .Results The NT‐proBNP ,CK‐MB ,Mb and TnT levels in the severe asphyxia group were significantly higher than those in the mild asphyxia group(P<0 .05) .The change of vari‐ous indexes levels in the observation group showed the ascending trend along with the asphyxia degree increase ,mo‐reover the levels in the observation group were significantly higher than those in the control group with statistical difference(P<0 .05) .Conclusion The NT‐proBNP level has significant clinical value in predicting the Mbcardial damage in neonates with asphyxia .关键词
N末端脑钠肽前体/新生儿/窒息/心肌损害Key words
NT-proBNP/neonates/asphyxia/myocardial damage引用本文复制引用
苑文雯,王晗,耿伟,何叶莉,朱剑功,李沛然,杨宁,李妍,郭桐生..N末端脑钠肽前体水平对预测窒息新生儿心肌损害的价值探讨[J].检验医学与临床,2014,(22):3112-3113,2.
