检验医学与临床Issue(23)：3263-3265,3.DOI:10.3969/j.issn.1672-9455.2014.23.013
抗菌药物治理及医务人员手卫生对肺炎克雷伯菌耐药性的影响
The effect of antimicrobial drug management and hand hygiene of the medical staff on the resistance of Klebsiella pneu-moniae
摘要
Abstract
Objective To explore the correlation between resistance of Klebsiella pneumoniae and the intensity of antimicrobial drug using ,the hand hygiene compliance of medical staff ,and provide reference for hospital infection control .Methods The correlation between resistance of Klebsiella pneumoniae ,isolated from samples of patients hospitalized in the Taihe Hospital Affiliated to Hubei University of Medicine from Jul .2011 to Dec .2013 ,and the in‐tensity of antimicrobial drug using ,the hand hygiene compliance of medical staff were statistically analyzed .Results The correlation coefficients between the rate of β‐lactam ,ceftazidime and gentamicin resistance in Klebsiella pneu‐moniae and the intensity of antimicrobial drug using were 0 .89 ,0 .87 ,and 0 .90 ,with statistically significant differ‐ences(P<0 .05) .The correlation coefficients between the separation of ESBL‐producing Klebsiella pneumoniae ,the rate of amoxicillin/clavulanic acid‐resistance and the hand hygiene compliance rate were -0 .90 and -0 .88 ,with sta‐tistically significant differences(P<0 .05) .Conclusion Regulating the use of antimicrobial drug and improving the hand hygiene compliance could reduce the resistance of Klebsiella pneumniae .关键词
抗菌药物/细菌耐药/手卫生/肺炎克雷伯菌/医院感染Key words
antimicrobial drug/bacterial resistance/hand hygiene/Klebsiella pneumniae/nosocomial infection引用本文复制引用
谢多双,张玉玲,胡荍,符湘云,王惠芳,罗清钦,向利丽..抗菌药物治理及医务人员手卫生对肺炎克雷伯菌耐药性的影响[J].检验医学与临床,2014,(23):3263-3265,3.基金项目
湖北省教育厅科研项目（B20112119）；湖北省十堰市科学技术研究与开发项目（2010st16）；湖北医药学院附属太和医院博士科研启动项目（2011QD03）。 （）
