检验医学与临床Issue(1)：66-67,70,3.DOI:10.3969/j.issn.1672-9455.2015.01.025
米氮平与草酸艾司西酞普兰治疗老年期抑郁症的对照观察
Control observation of mirtazapine and escitalopram oxalate for treating senile depression
陈浩 1刘京惠1
作者信息
- 1. 北京市朝阳区第三医院老年病房 100121
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of mirtazapine combined with escitalopram oxalate for treating senile depression .Methods 64 cases of senile depression conforming to the CCMD‐3 diagnostic criteria of depression were randomly divided into two groups and treated by mirtazapine and escitalopram oxalate respectively . The Hamilton Depression Scale(HAMD) and the treatment emergent symptom scale(TESS) were adopted to evalu‐ate the efficacy and the adverse reactions before treatment and at 1 ,2 ,4 ,6 weekend after treatment .Results The HAMD scores after 1 week in the mirtazapine group and the escitalopram oxalate group were decreased significantly , and the difference had statistical significance (P<0 .01) ,the HAMD scores at 1 weekend in the mirtazapine group were lower than those in the escitalopram oxalate group ,but the difference had no statistical significance(P>0 .05);the adverse reactions of mirtazapine were mainly dizziness ,drowsiness ,constipation ,increased appetite and weight gain ,which of escitalopram oxalate were mainly nausea and vomiting ,sweating ,insomnia and headache .Conclusion Mirtazapine and escitalopram oxalate have the similar efficacy for treating senile depression .关键词
米氮平/草酸艾司西酞普兰/老年/抑郁症Key words
mirtazapine/escitalopram oxalate/elderly/depression引用本文复制引用
陈浩,刘京惠..米氮平与草酸艾司西酞普兰治疗老年期抑郁症的对照观察[J].检验医学与临床,2015,(1):66-67,70,3.
