检验医学与临床Issue(2)：184-185,2.DOI:10.3969/j.issn.1672-9455.2015.02.018
降钙素原与C反应蛋白及白细胞介素-6联合检测在慢性乙型肝炎中的临床意义
Study on clinical significance of combined detection of PCT,CRP and IL-6 in chronic hepatitis B
苑文雯 1王晗 1何叶莉 1耿伟 1朱剑功 1李沛然 1杨宁 1李妍 1郭桐生1
作者信息
- 1. 中国人民解放军第三○二医院临床检验医学中心，北京 100039
- 折叠
摘要
Abstract
Objective To investigate the significance of PCT ,CRP and IL‐6 in the diagnosis and treatment of chronic hepatitis B(CHB) .Methods 60 cases of CHB treated in our hospital from May 2013 to March 2014 were collected as the observation group;at the same time period ,60 individuals with healthy physical examination were se‐lected as the control group .The serum CRP ,PCT and IL‐6 levels were detected and their significance in the diagnosis and treatment of CHB was analyzed .Results The CRP ,PCT ,IL‐6 levels in the observation group were (10 .7 ± 6 .8) mg/L ,(11 .2 ± 6 .1)μg/L and (253 .2 ± 45 .1)ng/L respectively ,which were significantly higher than (3 .3 ± 1 .0) mg/L ,(1 .2 ± 0 .5)μg/L and (64 .5 ± 10 .1)ng/L in the control group ,the differences between the two groups were statistically significant (P<0 .05) .The ROC curve analysis results showed that the sensitivity of CRP was 56 .9%and its specificity w as 70 .6% ;the sensitivity of IL‐6 w as 92 .3% and its specificity w as 95 .5% ;the sensitivity of PCT was 67 .5% and its specificity was 85 .0% .Conclusion The combined detection of PCT ,CRP and IL‐6 has very important clinical value in the diagnosis and treatment of CHB .关键词
慢性乙型肝炎/降钙素原/C反应蛋白/白细胞介素-6Key words
chronic hepatitis B/PCT/CRP/IL-6引用本文复制引用
苑文雯,王晗,何叶莉,耿伟,朱剑功,李沛然,杨宁,李妍,郭桐生..降钙素原与C反应蛋白及白细胞介素-6联合检测在慢性乙型肝炎中的临床意义[J].检验医学与临床,2015,(2):184-185,2.
