检验医学与临床Issue(4):460-462,3.DOI:10.3969/j.issn.1672-9455.2015.04.011
2011~2013年宁夏某院烧伤科病原菌分布及耐药性分析
Distribution and drug resistance of pathogens in burn department of a hospital in Ningxia from 2011 to 2013
摘要
Abstract
Objective To explore the distribution and drug susceptibility of pathogens causing infections of the patients in the burn department so as to guide reasonable use of antibiotics and control bacterial infection effectively . Methods To analyze retrospectively the distribution characteristic and drug resistant status of bacterial with positive result of bacterial culture in burn department from Jan 2011 to Dec 2013 .Results A total of 2 587 strains of patho‐gens were isolated from the patients of burn department ,there were 832 (32 .1% ) strains of gram‐negative bacteria , among which the top three isolated species were Enterobacter cloacae(E .cloacae) ,Acinetobacter baumannii(E .bau‐manni) and Escherichia coli(E .coli) ,accounting for 9 .3% ,6 .4% ,5 .2% respectively .The drug susceptibility rates of the E .cloacae to ampicillin ,cefazolin ,piperacillin ,cefoxitin and compound sulfcmethoxazole were 62 .9% ,100 .0% , 37 .5% ,100 .0% ,98 .3% ,respectively .The drug resistance rate of A .baumannii to most antimicrobials were over 60 .0% .The drug susceptibility rates of the E .coli to ampicillin ,amikacin ,levofloxacin were 91 .8% ,4 .1% ,56 .8% , respectively .There were 1 728(66 .8% ) strains of gram‐positive bacteria ,among which the highest isolated pathogens were Staphylococcus aureus(S .aureus) and Staphylococcus epidermidis (S .epidermidis) ,accounting for 21 .5% , 9 .4% ,respectively .The drug resistance rate of S .aureus to most antimicrobials were more than 70 .0% .The drug re‐sistance rate of S .epidermidis to most antimicrobial were more than 40 .0% .There was 27(1 .1% ) strains of fungi , among which the main pathogens was Candida albicans .Conclusion There are a variety of infection in the patients of burn department ,the main pathogens was Staphylococcus aureus ,the drug resistance rates of the pathogens to the commonly used antibiotics in the burn department are high ,and most strains shows multi‐drug resistance .Therefore , it is necessary to strengthen the monitoring of the drug resistance and guide the use of antibiotics .关键词
病原菌/抗菌药物/耐药性Key words
pathogen/antibiotic/drug-resistance引用本文复制引用
殷国民,刘自军,董辉,林茹,魏军,赵志军..2011~2013年宁夏某院烧伤科病原菌分布及耐药性分析[J].检验医学与临床,2015,(4):460-462,3.基金项目
宁夏回族自治区科技支撑计划项目(2013)。 ()