检验医学与临床Issue(5)：654-655,658,3.DOI:10.3969/j.issn.1672-9455.2015.05.029
心肌标志物联合检测在急性心肌梗死早期诊断中的应用价值
Application value of myocardial markers combined detection in early diagnosis of acute myocardial infarction
黄祥丽1
作者信息
- 1. 湖北省荆门市第一人民医院检验科 448000
- 折叠
摘要
Abstract
Objective To investigate the application of combined detection of high sensitive C reactive protein (hs‐CRP) ,cardiac troponin I (cTnI) and creatine kinase isoenzyme (CK‐MB) in the early diagnosis of acute myocar‐dial infarction .Methods 106 inpatients with type 2 mellitus diabetes (T2DM ) complicating myocardial infarction in our hospital from Jan .2010 to Dec .2013 were selected .Among them ,60 cases of myocardial infarction with typical symptoms were included as the control group and 46 cases of myocardial infarction with atypical symptoms were in‐cluded as the observation group .The changes of serum hs‐CRP ,cTnI and CK‐MB levels after onset of disease were dynamically monitored and the levels of various indexes at different time points were compared between two groups . Results The levels of serum hs‐CRP ,cTnI and CK‐MB at different time points had no statistical differences between the two groups (P>0 .05);the serum CK‐MB level in the two groups started to increase at 3 -12 h after onset , reached the peak at 24-48 h and recovered to normal level on 3-5 d;the serum hs‐CRP started to increase at 3 h af‐ter onset ,always maintained the high level and started to decrease after 3 -5 d;the serum hs‐CRP level in the two groups started to increase at 3-6 h after onset ,reached the peak at 12-24 h ,always maintained the high level and started to decrease after 5 d .Conclusion The combined detection of CK‐MB ,hs‐CRP and cTnI could be conducive to the early diagnosis of acute myocardial infarction ,especially increases the diagnostic rate in the patients with unappar‐ent symptoms and avoids misdiagnosis and missed diagnosis .关键词
心肌标志物/急性心肌梗死/联合检测Key words
cardiac markers/acute myocardial infarction/combined detection引用本文复制引用
黄祥丽..心肌标志物联合检测在急性心肌梗死早期诊断中的应用价值[J].检验医学与临床,2015,(5):654-655,658,3.
