检验医学与临床Issue(6)：732-733,736,3.DOI:10.3969/j.issn.1672-9455.2015.06.005
肌钙蛋白I与肌酸激酶同工酶在老年人急性心肌梗死中的应用价值
Aapplication value of cTnI and CK-MB in elderly patients with acute myocardial infarction
摘要
Abstract
Objective To study the diagnostic value of cardiac troponin I (cTnI) ,creatine kinase isoenzyme MB (CK‐MB) in elderly acute myocardial infarction(AMI) .Methods 106 elderly patients with AMI from Jan .2012 to Jun .2014 were selected as the AMI group ,68 elderly patients with chest pain as the chest pain group and 64 eld‐erly individuals of healthy physical examination as the healthy control group .The effect of cTnI and CK‐MB detection on the diagnosis of AMI ,and the changes of cTnI and CK‐MB in different periods after AMI occurrence were re‐searched .Results The levels and positive rates of serum cTnI and CK‐MB were higher than those in the chest pain group and the healthy control group ,the differences were statistically significant (P<0 .05);the sensitivity ,specifici‐ty and Jorden index of cTnI for the diagnosis of AMI were 92 .2% ,94 .7% and 0 .869 respectively ,which of CK‐MB were 87 .4% ,90 .9% and 0 .783 respectively ,the sensitivity ,specificity and Jorden index of the combined detection of these two indexes were increased to some extent ;the levels of cTnI and CK‐MB during 12 h to 1 d after admission were highest and then decreased .Conclusion The combination detection of cTnI and CK‐MB could have important significance to the early diagnosis and treatment of AMI ,which may be suitable for the promotion and application in the primary level hospitals .关键词
急性心肌梗死/肌钙蛋白I/肌酸激酶同工酶/胸痛Key words
acute myocardial infarction/troponin I/creatine kinase isoenzyme/chest pain引用本文复制引用
刘艳,王辉..肌钙蛋白I与肌酸激酶同工酶在老年人急性心肌梗死中的应用价值[J].检验医学与临床,2015,(6):732-733,736,3.基金项目
上海市科学技术委员会科研项目（11DZ1931500）。 （）
