检验医学与临床Issue(6)：799-800,2.DOI:10.3969/j.issn.1672-9455.2015.06.032
糖化血红蛋白与糖尿病及其并发症的相关性研究
Research on correlation between glycosylated hemoglobin with diabetes and its complications
马志忠 1王杏林2
作者信息
- 1. 云南省昆明市寻甸回族彝族自治县中医院 检验科 655200
- 2. 云南省昆明市寻甸回族彝族自治县中医院 内科 655200
- 折叠
摘要
Abstract
Objective To investigate the correlation between the glycosylated hemoglobin (HbA1c) level change with the blood glucose level and the corresponding complications in patients with diabetes mellitus(DM ) . Methods 215 cases of type 2 diabetes mellitus (T2DM ) from Jan .2012 to Jan .2014 were selected as the DM group and divided into the complicating hypertension group(70 cases) ,complicating hyperlipidemia group(19 cases) ,com‐plicating diabetic nephropathy(DN) group(21 cases) ,complicating peripheral neuropathy group (18 cases) ,complica‐ting bone fracture group(22 cases) and non‐complication group(87 cases) .In addition ,contemporaneous 215 individu‐als of healthy physical examination were selected as the healthy control group .The fasting venous blood in all the re‐search subjects was collected for detecting HbA1c and fasting plasma glucose(FPG) levels .The comparative analysis was conducted .Results The plasma HbA1c level in the DM group was higher than that in the control group ,the difference between them was statistical significant(P<0 .01);the plasma HbA1c level in the male DM patients was slightly higher than that in the female patients ,but the difference between them had no statistical significance(P>0 .05);moreover ,the plasma HbA1c level had no statistical difference between the different complication groups and the non‐complication group(P> 0 .05) .The plasma HbA1c level in the non‐complication patients and the patients with complications showed the increasing trend with the FPG level increase .Conclusion The HbA1c detection could accurately reflect the control status of the blood glucose level ,its clinical application could have an important value for the prevention ,diagnosis and control of DM ,but its prompt and preventive role for DM related complications has not been found .关键词
糖尿病/并发症/糖化血红蛋白/实验诊断Key words
diabetes mellitus/complication/glycated hemoglobin/laboratory diagnosis引用本文复制引用
马志忠,王杏林..糖化血红蛋白与糖尿病及其并发症的相关性研究[J].检验医学与临床,2015,(6):799-800,2.
