检验医学与临床Issue(6)：803-804,2.DOI:10.3969/j.issn.1672-9455.2015.06.034
血清CEA、CA19-9及铁蛋白联合检测在胰腺癌诊断中的价值
Value of combination detection of serum CEA,CA19-9 and ferritin in diagnosing pancreatic cancer
摘要
Abstract
Objective To investigate the value of the combination detection of serum CEA ,CA19‐9 and ferritin in the diagnosis of pancreatic cancer .Methods 64 patients conducted pancreatic cancer(pancreatic caner group) ,oth‐er 36 patients with chronic pancreatitis (chronic pancreatitis group) and 42 healthy persons conducted physical exam‐ination(control group) in our hospital from Jul .2011 to Apr .2013 were recruited for this study .Serum CEA ,CA19‐9 and ferritin expression levels in each group and detection sensitivity and specificity were compared .Results The ser‐um CEA ,CA19‐9 and ferritin expression levels in the pancreatic cancer group were significantly higher than those in the chronic pancreatitis group and the control group ,the differences had statistical significance(P<0 .05);the serum CEA ,CA19‐9 and ferritin expression levels had the statistical differences among different stages of TNM classifica‐tion (P<0 .05);the serum CEA ,CA19‐9 and ferritin expression levels in the patients with the survival period ≥6 months were lower than those in the patients with the survival period<6 months ,the differences had statistical sig‐nificance(P<0 .05);the sensitivity and the specificity of the combination detection of CEA ,CA19‐9 and ferritin were 87 .2% and 96 .1% respectively .Conclusion The combination detection of serum CEA ,CA19‐9 and ferritin could have important reference value for the diagnosis of pancreatic cancer .关键词
胰腺癌/癌胚抗原/糖类抗原19-9/铁蛋白Key words
pancreatic cancer/carcinoembryonic antigen(CEA)/carbohydrate antigen 19-9/ferritin引用本文复制引用
何淑霞,杨娜,刘东红..血清CEA、CA19-9及铁蛋白联合检测在胰腺癌诊断中的价值[J].检验医学与临床,2015,(6):803-804,2.
