检验医学与临床Issue(7)：885-887,3.DOI:10.3969/j.issn.1672-9455.2015.07.004
2型糖尿病合并视网膜病变患者凝血功能分析
Analysis of coagulation function in type 2 diabetes mellitus patients with diabetic retinopathy
摘要
Abstract
Objective To analysis the coagulation function in type 2 diabetes mellitus (T2DM ) patients with diabetic retinopathy (DR) .Methods A total of 154 cases of T2DM patients were enrolled and divided into non‐DR (NDR) group and DR group ,which was further divided into proliferative diabetic retinopathy (PDR) group and non‐PDR (NPDR) group ,according to the results of fundus examination .Clinical data was recorded ,and fasting blood glucose (FPG) ,glycated haemoglobin A1c (HbA1c% ) ,cholesterol (CHOL) ,triacylglycerol (TG) ,high density lipo‐protein (HDL ) ,low density lipoprotein (LDL ) ,prothrombin time (PT ) ,activated partial thromboplastin time (APTT ) ,thrombin time (TT ) ,fibrinogen (FIB) ,D‐dimer (DD) and fibrin degradation product (FDP) were detected and statistically analyzed .Results There were no statistical differences of FPG ,HbA1c ,CHOL ,TG ,HDL ,LDL , PT ,APTT ,TT ,DD and FDP among the three groups (P > 0 .05) .FIB level in DR group was higher than that in NDR group (P< 0 .05) ,but there was no statistical difference between NPDR group and PDR group (P > 0 .05) . Conclusion FIB might be a risk factor for the onset of DR .More attention should be paid for the FIB level in T2DM patients .关键词
2 型糖尿病/糖尿病视网膜病变/纤维蛋白原Key words
type 2 diabetic mellitus/diabetic retinopathy/fibrinogen引用本文复制引用
付广真,徐冰,侯军林,张曼..2型糖尿病合并视网膜病变患者凝血功能分析[J].检验医学与临床,2015,(7):885-887,3.基金项目
国家高技术研究发展计划（2014AA022304）；首都卫生发展科研专项项目（2011-2008-02）。 （）
