检验医学与临床Issue(7):919-920,2.DOI:10.3969/j.issn.1672-9455.2015.07.017
银屑病患者血清去氢表雄酮和硫酸去氢表雄酮水平的测定及临床意义
Detection and clinical significance of DHEA and DHEAS in serum from patients with psoriasis vulgaris
摘要
Abstract
Objective To explore the clinical significance of dehydroepiandrosterone (DHEA) and dehydroepi‐androsterone sulfate (DHEAS) in serum of patients with psoriasis vulgaris .Methods The serum DHEA/DHEA‐S levels of 154 psoriasis vulgaris patients and 154 controls were detected ,and their situation and clinical features were recorded and analyzed .Results Serum DHEA /DHEA‐S in psoriasis vulgaris patients were obviously lower than that in controls ,and the differences were statistically significant (P < 0 .05) .The serum levels of DHEA and DHEA‐S were both negatively correlated with course of psoriasis vulgaris (P< 0 .05) .The longer disease course was ,the low‐er serum levels of DHEA and DHEA‐S were .Conclusion Serum DHEA and DHEA‐S are related to the pathogenesis of psoriasis vulgaris .关键词
银屑病/去氢表雄酮/硫酸去氢表雄酮Key words
psoriasis/dehydroepiandrosterone/dehydroepiandrosterone sulfate引用本文复制引用
叶有兴,康丽,李莉..银屑病患者血清去氢表雄酮和硫酸去氢表雄酮水平的测定及临床意义[J].检验医学与临床,2015,(7):919-920,2.基金项目
广东省深圳市宝安区2014年度科技计划项目(20142477)。 ()