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银屑病患者血清去氢表雄酮和硫酸去氢表雄酮水平的测定及临床意义

叶有兴 康丽 李莉

检验医学与临床Issue(7):919-920,2.
检验医学与临床Issue(7):919-920,2.DOI:10.3969/j.issn.1672-9455.2015.07.017

银屑病患者血清去氢表雄酮和硫酸去氢表雄酮水平的测定及临床意义

Detection and clinical significance of DHEA and DHEAS in serum from patients with psoriasis vulgaris

叶有兴 1康丽 2李莉1

作者信息

  • 1. 广东省深圳市坪山新区人民医院皮肤科 518118
  • 2. 广东省深圳市沙井人民医院 518105
  • 折叠

摘要

Abstract

Objective To explore the clinical significance of dehydroepiandrosterone (DHEA) and dehydroepi‐androsterone sulfate (DHEAS) in serum of patients with psoriasis vulgaris .Methods The serum DHEA/DHEA‐S levels of 154 psoriasis vulgaris patients and 154 controls were detected ,and their situation and clinical features were recorded and analyzed .Results Serum DHEA /DHEA‐S in psoriasis vulgaris patients were obviously lower than that in controls ,and the differences were statistically significant (P < 0 .05) .The serum levels of DHEA and DHEA‐S were both negatively correlated with course of psoriasis vulgaris (P< 0 .05) .The longer disease course was ,the low‐er serum levels of DHEA and DHEA‐S were .Conclusion Serum DHEA and DHEA‐S are related to the pathogenesis of psoriasis vulgaris .

关键词

银屑病/去氢表雄酮/硫酸去氢表雄酮

Key words

psoriasis/dehydroepiandrosterone/dehydroepiandrosterone sulfate

引用本文复制引用

叶有兴,康丽,李莉..银屑病患者血清去氢表雄酮和硫酸去氢表雄酮水平的测定及临床意义[J].检验医学与临床,2015,(7):919-920,2.

基金项目

广东省深圳市宝安区2014年度科技计划项目(20142477)。 ()

检验医学与临床

OACSTPCD

1672-9455

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