检验医学与临床Issue(7)：933-934,2.DOI:10.3969/j.issn.1672-9455.2015.07.023
甲状腺功能亢进症患者血清骨转换指标浓度变化研究
Changes of serum levels of bone turnover markers in patients with hyperthyroidism
孙永敏 1杨萍 1王鹏2
作者信息
- 1. 郑州大学第二附属医院核医学科，郑州 450014
- 2. 河南省人民医院核医学科，郑州 450003
- 折叠
摘要
Abstract
Objective To investigate the changes of serum levels of bone resorption marker (β‐Crosslaps) and bone formation marker (total pro‐collagen type Ⅰ N‐terminal peptide ,tPINP) in patients with hyperthyroidism . Methods Serum levels of β‐Crosslaps and tPINP were measured in 40 hyperthyroidism patients and 40 healthy indi‐viduals by using electro‐chemiluminescence immunoassay .Data of the two groups were statistically analyzed by using independent sample t‐test .Results Serum levels of β‐Crosslaps and tPINP in hyperthyroidism patients were (1 .17 ± 0 .69) and (160 .5 ± 137 .4) ng/mL respectively ,which were respectively higher than the (0 .61 ± 0 .20) and (49 .3 ± 14 .1) ng/mL in healthy individuals (P < 0 .01) .Conclusion High levels of thyroid hormones might speed up the bone metabolism ,then made the bone turnover processes actively in patients with hyperthyroidism .关键词
甲状腺功能亢进症/β-胶原特殊序列/总Ⅰ型前胶原氨基端延长肽Key words
Hyperthyroidism/β-Crosslaps/total pro-collagen type Ⅰ N-terminal peptide引用本文复制引用
孙永敏,杨萍,王鹏..甲状腺功能亢进症患者血清骨转换指标浓度变化研究[J].检验医学与临床,2015,(7):933-934,2.
