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肠球菌医院感染特征及新型抗菌药物耐药性研究

王敏 吴李培 万晓龙 韩叶 宣世海 茅敏 赵建春 周玉贵

检验医学与临床Issue(8):1081-1083,3.
检验医学与临床Issue(8):1081-1083,3.DOI:10.3969/j.issn.1672-9455.2015.08.021

肠球菌医院感染特征及新型抗菌药物耐药性研究

Characteristics of enterococcus causing nosocomial infection and the study with drug resistance to new antibiotic

王敏 1吴李培 1万晓龙 1韩叶 1宣世海 1茅敏 1赵建春 1周玉贵1

作者信息

  • 1. 南通大学附属东台医院检验科,江苏东台 224200
  • 折叠

摘要

Abstract

Objective To explore the distribution and resistance characteristics of enteroco‐ccus bacteria and offer guidance for rational administration and nosocomial infection .Methods Clinical specimens in our hospital from Jan 2011 to Dec 2013 were cultivated ,then the identification and drug sensitivity test were carried out .Results 140 strains of enterococcus were detected ,in which 99 strains (70 .7% )were from urine;Excrement enterococcus 71 strains (50 .7% ) ,60 in enterococcus strains (42 .9% ) ,9 other enterococcus strains(6 .4% );the drug of resistance rate of E .faecium to penicillin was 15 .0% ,ampicillin 12 .5% ,erythromycin 75 .0% ;while the drug of resistance rates of E .faecalis to penicillin ,ampicillin ,levofloxacin ,ciprofloxacin and erythromycin were more than 80 .0% ;E .faecium and E .faecalis were acutely sensitive to vancomycin and linezolid ,the drug of resistance rates of E .faecium and E . faecalis to vancomycin were 5 .0% ,4 .2% respectively ,linezolid were 8 .4% ,1 .4% respectively ,the drug of resistance rate of E .faecium to quinupristin/dalfopristin(100 .0% ) was more than E .faecalis(26 .7% ) ,resistant strains of dap‐tomycin have not been found so far .Conclusion Enterococcus was the predominant specie causing urinary tract infec‐tions ,and the detection rate of E .faecalis slightly greater than E .faecium ,the majority resistance to antimicrobial a‐gents of E .faecalis were more than E .faecium ;quinupristin、dalfopristin only has a higher sensitivity to E .faecalis;at the same time ,vancomycin ,linezolid and daptomycin keep high sensitivity to enterococcus .

关键词

肠球菌属/医院感染/抗菌药物/耐药性

Key words

enterococci/nosocomial infection/antibiotic/drug resistance

引用本文复制引用

王敏,吴李培,万晓龙,韩叶,宣世海,茅敏,赵建春,周玉贵..肠球菌医院感染特征及新型抗菌药物耐药性研究[J].检验医学与临床,2015,(8):1081-1083,3.

检验医学与临床

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1672-9455

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