检验医学与临床Issue(9)：1233-1234,1237,3.DOI:10.3969/j.issn.1672-9455.2015.09.021
糖化血红蛋白对前驱糖尿病诊断和监测的临床意义
Clinical significance of glycosylated hemoglobin on diagnosis and monitoring of prediabetes
李晓艳 1邱晓沛 2张洪 2刘星 2罗阳2
作者信息
- 1. 成都军区机关医院内分泌科 610011
- 2. 第三军医大学第一附属医院输血科，重庆 400038
- 折叠
摘要
Abstract
Objective To discuss the clinical significance of glycated hemoglobin in diagnosis and monitoring of pre‐diabetes mellitus(DM ) .Methods The fasting blood glucose ,2 h postprandial blood glucose and glycosylated he‐moglobin in 434 outpatients in the endocrinological clinic of the Institution Hospital of Chengdu Military Region were detected and the results were statistical analyzed .Results In the pre‐DM group(118 cases) ,the fasting blood glucose was(6 .48 ± 0 .52)mmol/L ,2 h postprandial blood glucose was(9 .55 ± 1 .38)mmol/L and glycosylated hemoglobin was(5 .83 ± 0 .22)% ;in the diabetes group(145 cases) ,the fasting blood glucose was(13 .81 ± 2 .12)mmol/L ,2 h postprandial blood glucose was(19 .33 ± 3 .79)mmol/L and glycosylated hemoglobin was(10 .12 ± 0 .45)% ;in the control group(171 cases) ,the fasting blood glucose was(5 .31 ± 0 .78)mmol/L ,2 h postprandial blood glucose was (6 .05 ± 1 .12) mmol/L and glycosylated hemoglobin was(4 .72 ± 0 .51)% ,the differences were statistically signifi‐cance(P<0 .05) .Glycosylated hemoglobin level was positively correlated with fast glucose and 2 h postprandial blood glucose (P<0 .05) .The sensitivity and specificity of glycated hemoglobin for diagnosing DM were 100 .0% and its sensitivity and specificity for diagnosing pre‐DM were 97 .5% and 100% respectively .Conclusion Glycated hemoglo‐bin can effectively differentiate diabetes from pre‐DM ,which has an important significance in the treatment and moni‐toring of DM .关键词
前驱糖尿病/空腹血糖/糖化血红蛋白/诊断Key words
pre-DM/fasting blood glucose/glycosylated hemoglobin/diagnosis引用本文复制引用
李晓艳,邱晓沛,张洪,刘星,罗阳..糖化血红蛋白对前驱糖尿病诊断和监测的临床意义[J].检验医学与临床,2015,(9):1233-1234,1237,3.
