检验医学与临床Issue(9)：1235-1237,3.DOI:10.3969/j.issn.1672-9455.2015.09.022
NP方案化疗及同步放疗治疗非小细胞肺癌的临床效果
Clinical effect of NP chemotherapy and synchronous radiotherapy for treating non-small cell lung cancer
戴文鑫 1吴智勇 1陈娟 1冯光球 1管频1
作者信息
摘要
Abstract
Objective To study the clinical effect of sequential adoptive immunity cells combined with chemo‐therapy of vinorelbine(N) and cis-platinum(P) and synchronous radiotherapy in the treatment of non‐small cell lung cancer(NSCLC) .Methods 60 patients with NSCLC were selected as the research subjects and randomly divided into the control group and the observation group .The control group adopted the NP chemotherapy+ synchronous radio‐therapy .On this basis the observation group was added with the adoptive immune cells therapy .The treatment effect , improvement of immune indexes before and after treatment ,improvement of the quality of life and occurrence situa‐tion of adverse reactions were observed and compared between the two groups .Results The total effective rate and clinical benefit rate of the observation group were significantly higher than those of the control group ,the improve‐ment situation of various immune indexes in the observation group were significantly superior to those in the control group ,the life quality Karnofsky score after treatent in the observation group were significantly better than those in the control group ,the differences were statistically significant(P< 0 .05);the incidence of adverse reactions had no statistically significant difference between the two groups (P>0 .05) .Conclusion Sequential adoptive immune cells combined with NP chemotherapy and radiotherapy has remarkable clinical effect for treating NSCLC ,the immune function is obviously improved ,which is worth clinical promotion and application .关键词
过继免疫细胞/长春瑞滨/顺铂/化疗/同步放疗/非小细胞肺癌Key words
adoptive immunity cells/vinorelbine/cisplatinum/chemotherapy/synchronous radiother-apy/non-small cell lung cancer引用本文复制引用
戴文鑫,吴智勇,陈娟,冯光球,管频..NP方案化疗及同步放疗治疗非小细胞肺癌的临床效果[J].检验医学与临床,2015,(9):1235-1237,3.
