摘要
Abstract
Objective To investigate the correlation between the BCG vaccination with the occurrence and se‐verity of neonatal pathological jaundice .Methods 200 neonates born in our hospital from January 2011 to December 2013 were selected ,including 85 cases of cesarean section and 115 cases of vaginal delivery .40 cases of BCG inocula‐tion at 48 h after cesarean section were classified as the group A ,45 cases of BCG vaccination on 5 d after cesearean section as the group B ,50 cases of BCG vaccination at 12 h after natural birth as the group C and 65cases of BCG vac‐cination on 3 d after birth as the group D .The occurrence rate and bilirubin peak of neonatal pathological jaundice were observed in various groups .Results (1)The occurrence rate of neonatal pathological jaundice in the group C was 68 .00% ,which was significantly higher than 35 .00% ,31 .11% and 30 .76% in the group A ,B and D ,the differ‐ences were statistically significant (χ21 =7 .256 ,χ22 =7 .998 ,χ23 =8 .115 ,P<0 .05);(2)The serum bilirubin peak value in the group C was (14 .98 ± 4 .86)mg/dL ,which was higher than (14 .33 ± 3 .55) ,(13 .91 ± 3 .08) ,(14 .02 ± 3 .09) mg/dL in the group A ,B and D ,the differences were statistically significant (t1 =6 .221 ,t2 =7 .018 ,t3 =6 .582 ,P<0 .05);(3)The serum bilirubin peak values in neonates with pathologic jaundice of the group A ,B ,C and D were (14 .98 ± 1 .76) ,(14 .61 ± 1 .56) ,(15 .76 ± 2 .05) ,(15 .76 ± 2 .05) mg/dL respectively ,the differences were statisti‐cally significant (F=10 .223 ,P<0 .05) .Conclusion The earlier of BCG vaccination time ,the higher of incidence and severity of neonatal pathological jaundice .关键词
卡介苗/新生儿/病理性黄疸Key words
BCG/neonate/pathological jaundice
