检验医学与临床Issue(9)：1271-1272,1275,3.DOI:10.3969/j.issn.1672-9455.2015.09.036
妊娠期血脂生理性变化趋势及正常参考值研究
Rescarch on normal reference values of blood lipid levels in pregnancy
何廷德 1刘武林2
作者信息
- 1. 重庆市涪陵区妇幼保健院 妇产科 408000
- 2. 重庆市涪陵区妇幼保健院 检验科 408000
- 折叠
摘要
Abstract
Objective To research the change trend of blood lipids during normal pregnancy for establishing the normal reference value ranges in normal pregnant women .Methods By using the prospective study ,492 normal pregnant women undergoing the prenatal examination and institutional delivery without cocurrent disease and compli‐cations in our hospital from June 2013 to June 2014 were selected and contemporaneous 156 non‐pregnant healthy women were selected as the controls for establishing the normal referencevalue ranges of blood lipids ,including TG , TC ,HDL ,LDL ,apo A ,apo B .The blood lipids of pregnant women were detected by adopting the enzymic method . The reference value range was expressed by median and two‐side limiting value .Its change trend wa sresearched by using t test .Results (1)The blood lipid levels during pregnancy in pregnant women were gradually increased with the gestational duration extending and reached the peak value till late pregnancy ,which in second trimester and late pregnancy were significantly higher than those in the early pregnant women and non‐pregnant women ,the differences were statistically significant (P<0 .05) ,but there was no statistical difference between the early pregnant women and non‐pregnant women (P>0 .05);the cholesterol and triglyceride levels in late pregnant women were 1 .5 times and 4 times of which in non‐pregnant women respectively .(2)Using the median and bilateral limiting value for expressing the blood lipid reference value in pregnancy ,the range of cholesterol(TC):3 .20 -6 .93 mmol/L in early pregnancy , 3 .04-8 .83 mmol/L in the second trimester of pregnancy and 3 .54 -9 .83 mmol/L in late pregnancy ;triglyceride (TG):0 .12-4 .53 mmol/L in early pregnancy ,0 .17-5 .30 mmol/L in the second trimester of pregnancy and 0 .13-6 .12 mmol/L in late pregnancy .Conclusion The blood lipid levels during pregnancy pregnancy in pregnant women are gradually increased with the pregancy duration ,demonstrate the significant differences during early ,middle and late pregnancy and reach the peak value till late pregnancy .Establishing the reference value ranges of blood lipids in pregnant women has a clinical significance .关键词
妊娠/血脂/参考值Key words
pregnancy/blood lipid/reference value引用本文复制引用
何廷德,刘武林..妊娠期血脂生理性变化趋势及正常参考值研究[J].检验医学与临床,2015,(9):1271-1272,1275,3.
