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肾脏相关标志物在评估妊娠高血压综合征肾损伤的研究

陈志晓 谢淑贤 陈金玲 陈国卫 利定建 吴修宇

检验医学与临床2015,Vol.12Issue(11):1542-1544,3.
检验医学与临床2015,Vol.12Issue(11):1542-1544,3.DOI:10.3969/j.issn.1672-9455.2015.11.019

肾脏相关标志物在评估妊娠高血压综合征肾损伤的研究

Clinica value of markers related kidney in assessing renal dysfunction in pregnancy induced hypertension women

陈志晓 1谢淑贤 1陈金玲 1陈国卫 1利定建 1吴修宇1

作者信息

  • 1. 广东省阳江市人民医院检验科 529500
  • 折叠

摘要

Abstract

Objective To evaluate the significance of the serum cystatin C (Cys-C) Homocysteine(Hcy) ,24 h urinary protein excretion(24 h-UPE) ,UREA and Scr in assessing renal dysfunction in Pregnancy induced hyperten-sion(PIH) women .Methods Biochemistry was used to evaluate the level of Cys-C ,Hcy ,24 h-UPE ,UREA and Scr in 133 PIH patients (study group) who were divided into 3 groups ,the low group ,medium group and severe group , compared with 30 normal pregnant women(control group) .Results The concentrations of Cys-C ,Hcy ,24 h-UPE , UREA and Scr were significantly higher in the low PIH group than in the control group ,all in the medium PIH group and severe PIH group higher in the control group and low PIH group .Correlation analyses demonstrated significant correlations between Cys-C and 24 h-UPE in all the 133 pregnant women ,r=0 .780(P<0 .01) .Conclusion Cys-C , Hcy ,24 h-UPE ,UREA and Scr can reflect the degree of renal function damage in patients with PIH .

关键词

妊高征/胱抑素C/同型半胱氨酸/24小时尿蛋白定量

Key words

pregnancy induced hypertension/serum cystatin C/homocysteine/24 h urinary protein ex-cretion

引用本文复制引用

陈志晓,谢淑贤,陈金玲,陈国卫,利定建,吴修宇..肾脏相关标志物在评估妊娠高血压综合征肾损伤的研究[J].检验医学与临床,2015,12(11):1542-1544,3.

基金项目

广东省阳江市科技项目[卫(2013 )60 ]. (2013 )

检验医学与临床

OACSTPCD

1672-9455

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