检验医学与临床Issue(12)：1670-1671,1675,3.DOI:10.3969/j.issn.1672-9455.2015.12.005
丁苯酞注射液联合阿托伐他汀强化治疗急性脑梗死的临床研究
Clinical analysis about butylphthalide and sodium chloride injection combined with atorvastatin on acute cerebral infarc- tion
摘要
Abstract
Objective To evaluate the efficacy and safety of butylphthalide and sodium chloride injection in a‐cute cerebral infarction .Methods 84 cases of acute cerebral infarction were diveded into teo groups .The efficacy and safety of patients were compared in therapy group (n=42) and control group (n=42) of period of treatment for 14 days .All patients were given oral drugs (Aspirin1 100 mg/day ,atorvastatin 80 mg/day) and Ginkgo leaf extract and Dipyridamole injection (20 ml/day) .Therapy group also were given butylphthalide and sodium chloride injection . NIHSS、Barthel scale and safe indexes in two groups were analyzed .Results Two groups were no statistic difference with patient feature ,disease history and first scales .The total clinical efficacy scale in therapy and control were 7 .6 and 10 .8 ,65 .71 and 50 .14 .There were statistic difference in two groups (P<0 .05) .Total efficacy were obvious sta‐tistic difference (29 .63% ,58 .26% ,P<0 .05) .Transaminase had mild high in 1 case with normal recovery after one follow‐up month .Adverse reactions was low(2 .5% ) .Conclusion The therapy with butylphthalide and sodium chlo‐ride injection was effective and safe to acute cerebral infarction .关键词
丁苯酞注射液/脑梗死/美国国立卫生研究院卒中量表评分/日常生活活动能力量表评分Key words
butylphthalide/cerebral infarction/NIHSS score/Barthel score引用本文复制引用
栾松,黄晓勇,刘娟,李浩东,范永新,刘猛,朱月敏..丁苯酞注射液联合阿托伐他汀强化治疗急性脑梗死的临床研究[J].检验医学与临床,2015,(12):1670-1671,1675,3.基金项目
河北省科技支撑计划项目（20130687）。 （）
